In the book of Mice and Men both their are two guys who have a dream. Like all dreams you must go through obstacle to achieve their goal. This quote "Some of the best laid plans of mice and men often go awry," is used in reference to the book of Mice and Men. To prove this quote I will show you three citations from the book. The quote relates to the novel mainly because …showed first 75 words of 554 total…

…showed last 75 words of 554 total…awry when George is force to kill Lennie. George had to kill Lennie because he did not want anyone else to hurt him. So now George is on his own. In conclusion the quote is really saying that a person can do everything possible to make their plans perfect. There will always be something that is going will cause you to alter your plans. George had to alter his plans cause he was now alone.